Chronic Inflammation & Oxidative Stress
Serving size : 1 capsule
Servings per bottle : 60 (500mg x 60 Bovine Capsules)
Ingredient List : Flax Seeds, Sesame Seeds, Turmeric Rhizomes, Chia Seeds, Grape Seeds
All natural and highest quality ingredients. Contains no drugs, chemicals, anti-caking and flow agents, stabilisers and volume fillers.
Adults : Take 2-3 capsules with meals twice a day or as directed by healthcare professionals.
Precaution : Not recommended for pregnant & Breast Feeding Women. For Adult use only.
Store below 30 C. Protect from light & moisture.
Keep out of reach of children.
|Senescence And Premature Ageing Oxi-inflammation in the process of oxi-inflamm-aging belongs to nonresolving inflammation and oxidative stress. Oxi-Inflamm-aging is a determinant of the speed of the aging process and of lifespan and is highly related to Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, atherosclerosis, heart disease, age-related macular degeneration, type II diabetes, insulin resistance, cancer, and other diseases. Oxi-inflamm-aging also increases morbidity and mortality, significantly harming the health of patients, and causes a decline in the quality of life of patients. Chronic, subclinical inflammation and oxidative stress coexist in the process of oxi-inflamm-aging.|
|Chronic Kidney Disease & End Stage Renal Disease
Chronic kidney disease includes conditions that damage your kidneys and decrease their ability to keep you healthy by filtering wastes from your blood. If kidney disease worsens, wastes can build to high levels in your blood and make you feel sick. You may develop complications like:
|Persistent Inflammatory Asthma
Asthma is a chronic inflammatory disorder of the airways. The chronic inflammation is associated with airway hyperresponsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing. Common symptoms of asthma include:
|Chronic Obstructive Pulmonary Diseases (COPD) Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease that causes obstructed airflow from the lungs. Symptoms include breathing difficulty, cough, mucus (sputum) production and wheezing. It's typically caused by long-term exposure to irritating gases or particulate matter, most often from cigarette smoke. People with COPD are at increased risk of developing heart disease, lung cancer and a variety of other conditions. COPD is a progressive disease that gets worse over time if left untreated. Emphysema and chronic bronchitis are the two most common conditions that contribute to COPD. These two conditions usually occur together and can vary in severity among individuals with COPD. Chronic bronchitis is inflammation of the lining of the bronchial tubes, which carry air to and from the air sacs (alveoli) of the lungs. It's characterized by daily cough and mucus (sputum) production. Emphysema is a condition in which the alveoli at the end of the smallest air passages (bronchioles) of the lungs are destroyed as a result of damaging exposure to cigarette smoke and other irritating gases and particulate matter.|
|Alzheimer’s Disease Alzheimer’s disease (AD) is a devastating age-related neurodegenerative disorder with an alarming increasing prevalence. Over the last years, it became increasingly clear that chronic inflammation is one of the detrimental factors that can contribute to the disease. Systemic inflammation is believed to induce reactive, proinflammatory microglia and astrocytic phenotypes which can promote tau hyperphosphorylation, β-amyloid oligomerization, complement activation, and the breakdown of neurotransmitters into potentially harmful bioactive metabolites. Together, these molecular changes are believed initiate or exacerbate neurodegenerative processes that can eventually lead to cognitive decline and dementia in vulnerable older adults. Alzheimer’s disease is the most common type of dementia. It is a progressive disease beginning with mild memory loss and possibly leading to loss of the ability to carry on a conversation and respond to the environment. Alzheimer’s disease involves parts of the brain that control thought, memory, and language. It can seriously affect a person’s ability to carry out daily activities.|
|Parkinson’s Disease Parkinson disease (PD) is a degenerative condition of the brain associated with motor symptoms (slow movement, tremor, rigidity and imbalance) and other complications including cognitive impairment, mental health disorders, sleep disorders and pain and sensory disturbances. Chronic Inflammation and PD Extensive evidence in human samples and from animal models support the involvement of inflammation in the development of PD. However, the exact trigger for this response remains unclear. While inflammation might be the consequence of ongoing neuronal cell death in PD, it is also likely that misfolded α-Syn might play a direct role. In addition to the well-documented microgliosis and astrogliosis in PD brains, peripheral inflammation and PD-risk-associated genes support an important contribution of the chronic inflammatory response on the progression of this neurodegenerative disease.|
|Atheroscrelosis (ACVD) Inflammation and oxidative stress participates in all stages of ACVD; all risk factors of atherosclerosis as well as the disease progression have been shown to elicit oxi-inflammatory response. Clinical trials, laboratory experiments on animals and tissues in conjunction with population studies have yielded vital clues that lend credence to the claim that ACVD is a chronic oxi-inflammatory disease. ACVD does not result merely from the build up of lipids: macrophage colony-stimulating factor plays a key role in the regulation of the amounts of macrophages and monocytes and in lesion formation but lipids and other molecules have minimal effect on atherosclerosis development.|
|Diabetes Mellitus Type 2 Recent research suggests that inflammation inside the body plays a role in the development of type 2 diabetes. With type 2 diabetes, inflammation is internal. Researchers discovered that in people with type 2 diabetes, cytokine (inflammatory molecules) levels are elevated inside fat tissue. As type 2 diabetes starts to develop, the body becomes less sensitive to insulin and the resulting insulin resistance also leads to inflammation. A vicious cycle can result, with more inflammation causing more insulin resistance and vice versa. Blood sugar levels creep higher and higher, eventually resulting in type 2 diabetes and increasing its severity. The proposed mechanisms to explain impaired insulin secretion and sensitivity in type 2 diabetes include oxidative stress, endoplasmic reticulum stress, amyloid deposition in the pancreas, ectopic lipid deposition in muscle, liver and pancreas, and lipotoxicity and glucotoxicity. All these cellular stresses may induce an inflammatory response or are exacerbated by or associated with inflammation.|
|Cancer and Inflammation Inflammation predisposes to the development of cancer and promotes all stages of tumorigenesis. Cancer cells as well as surrounding stromal and inflammatory cells engage in well-orchestrated reciprocal interactions to form an inflammatory tumor microenvironment (TME). Cells within the TME are highly plastic, continuously changing their phenotypic and functional characteristics. Oxidative stress can lead to chronic inflammation, which in turn could mediate most chronic diseases including cancer, diabetes, cardiovascular, neurological and pulmonary diseases. Oxidative stress can activate a variety of transcription factors including NF-κB, AP-1, p53, HIF-1α, PPAR-γ, β-catenin/Wnt, and Nrf2. Activation of these transcription factors can lead to the expression of over 500 different genes, including those for growth factors, inflammatory cytokines, chemokines, cell cycle regulatory molecules, and anti-inflammatory molecules. How oxidative stress activates inflammatory pathways leading to transformation of a normal cell to tumor cell, tumor cell survival, proliferation, chemoresistance, radioresistance, invasion, angiogenesis and stem cell survival is the focus of this review. Oxidative stress, chronic inflammation, and cancer are closely linked.|
|1.Flax Seeds Core – riches natural plant source of balanced Omega 3-6-9 FA, polyphenol, lignans, bioflavonoids & phytosterol|
|2.Grape Seeds Standardised Extract - Rich in Resveratrol (red wine essence), OPC (oligomeric proanthocyanidins), flavonoids, linoleic acid,|
|3.Turmeric Standardised Extract – Curcumin, powerful anti-inflammatory & antioxidant|
|4.Chia Seeds – rich in plant phenolic acid & omega-3 FA|
|5.Sesame Seeds – contains Sesamin, powerfulnatural Antinociceptive (paintkiller) and Anti-Inflammatory|
Please consult your pharmacist or doctor before taking this product.
The information above has not been evaluated or approved by the Food and Drug Administration (FDA) and is not necessarily based on scientific evidence from any source. These products are intended to support general wellbeing and are not intended to treat, diagnose, mitigate, prevent, or cure any condition or disease. Please consult healthcare professionals for any medical, health conditions or injury. If conditions persist, please seek advice from your medical doctor.